Oxytocin hmoovyog ib yam tshuaj uas tsim nyob rau hauv lub hypothalamus thiab feem ntau hu ua "kev sib raug zoo hormone" los yog "hormone hlub" vim nws lub luag hauj lwm tseem ceeb hauv kev txhim kho kev xav thiab kev xav ntawm cov tib neeg. Nws yog qhov tshwj xeeb tshaj yog paub txog nws txoj haujlwm thaum yug menyuam thiab pub niam mis, txhawb cov niam- kev sib raug zoo ntawm menyuam yaus thiab ua kom yooj yim rau cov txheej txheem hauv tsev laus los ntawm kev ua kom lub tsev menyuam thiab pab cov mis nyuj. Kev tshawb fawb kuj tau qhia oxytocin txoj kev koom tes hauv tib neeg kev sib deev arousal thiab kev ntseeg siab nyob rau hauv kev sib raug zoo romantic.
Shaanxi Medibridge Biotech Co., Ltd., Ltd. muab cov ntaub ntawv no raws li kev tshawb fawb - qib hmoov lossis customized vial filling. Txhua pawg tuaj yeem txhawb nqa nrog HPLC cov ntaub ntawv purity, LC-MS tus kheej kuaj, COA, thiab cov ntaub ntawv ntim tau pom zoo. Cov khoom yog muab rau kev tshawb fawb siv xwb.
COA
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Khoom npe |
CAS Nr |
Batch Number |
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Oxytocin hmoov |
50-56-6 |
MB2603051545 |
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Hnub tim tsim khoom |
Hnub Soj Ntsuam |
Hnub Kawg |
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2026/3/05 |
2026/3/06 |
2028/3/05 |
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Qauv Qty Puag |
Ntim |
Txoj Kev Xeem |
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1.25 KGS |
25GS / lub raj mis |
HPLC |
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Yam khoom |
Txuj |
Cov txiaj ntsig |
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Purity |
Ntau dua lossis sib npaug li 98% |
99.25% |
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Solubility |
Soluble hauv dej |
Ua raws |
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Clarity thiab xim ntawm kev daws |
Ntshiab thiab tsis muaj xim |
Ua raws |
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Sodium ntsev |
<5.0% |
1.32% |
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Methanol |
Tsawg dua lossis sib npaug li 0.3% |
Ua raws |
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Isopropanol |
Tsawg dua lossis sib npaug li 0.5% |
0.15% |
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Cov tshuaj acetonitrile |
Tsawg dua lossis sib npaug li 0.041% |
0.02% |
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Methylene Chloride |
Tsawg dua lossis sib npaug li 0.06% |
0.03% |
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N,N{0}}Dimethylformamide |
Tsawg dua lossis sib npaug li 0.088% |
Ua raws |
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Triethylamine |
Tsawg dua lossis sib npaug li 0.032% |
Ua raws |
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Tert -butyl methyl ether |
Tsawg dua lossis sib npaug li 0.5% |
0.17% |
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Microbial txwv |
Tag nrho cov kab mob aerobic<100 CFU/g |
<50 CFU/g |
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Tag nrho cov poov xab & pwm<50 CFU/g |
<10 CFU/g |
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Cia |
Khaws rau hauv qhov chaw tsaus thiab txias qhuav (2 txog 8 degree) |
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Xaus |
Cov batch ua raws li IN-HOUSE tus qauv |
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Mechanism ntawm Action
Oxytocin peptide ua haujlwm los ntawm kev khi cov oxytocin receptor, uas ua rau cov xovtooj ntawm - qhia txoj hauv kev hauv cov ntaub so ntswg thiab cov neural circuits. Nyob rau hauv lub tsev menyuam du nqaij, oxytocin receptor signaling tsub kom intracellular calcium thiab txhawb contraction.
- Oxytocin Receptor Activity thiab Cell Signaling
Cov oxytocin receptor yog G protein-coupled receptor uas feem ntau yog khub niam txiv rau Gq/11-tsev neeg teeb liab, ua rau txoj hauv kev hauv nruab nrog cev koom nrog kev txhawb nqa calcium. Nyob rau hauv lub tsev menyuam, oxytocin binding activates phospholipase C signaling, inositol triphosphate kev ua, thiab calcium tso tawm, uas txhawb nqa cov leeg nqaij.
Oxytocin receptor qhia hloov pauv thoob cov ntaub so ntswg thiab lub cev lub cev. Thaum cev xeeb tub lig, uterine rhiab heev rau oxytocin nce, uas yog ib qho laj thawj uas sau npe siv kev kho mob yuav tsum tau ceev faj, tshuaj xyuas, thiab kev txiav txim siab kho mob.
- Central Nervous System thiab Peripheral Oxytocin Effects
Oxytocin muaj cov teebmeem peripheral nyob rau hauv lub tsev menyuam thiab lub mis, tab sis oxytocin kuj modulates central paj hlwb circuits. Intranasal oxytocin kev tshawb fawb feem ntau tsom rau kev paub txog kev sib raug zoo vim tias txoj hauv kev yog npaj los cuam tshuam rau hauv nruab nrab oxytocin signaling ncaj qha tshaj li peripheral txhaj.
Hauv tib neeg, cov kev sim thaum ntxov tau tshaj tawm tias intranasal oxytocin cuam tshuam kev ntseeg tus cwj pwm, thiab cov kev tshawb fawb neuroimaging tau qhia txog kev hloov pauv hauv amygdala cov lus teb rau lub ntsej muag lub siab. Cov kev tshawb pom no yog cov cim tseem ceeb ntawm kev tshawb fawb, tab sis lawv tsis ua rau oxytocin yog ib qho kev qhia dav dav - lub hom phiaj txhim kho kev sib raug zoo.
Oxytocin Thiab Uterine Contractions
Thaum lub sijhawm ua haujlwm, thaum tus menyuam hauv plab lub cev (feem ntau lub taub hau) thawb tawm tsam koj lub tsev menyuam, cov hlab ntsha ntawm qhov kev txhawb nqa no mus rau koj lub hlwb thiab txhawb koj lub caj pas pituitary kom tso tawm oxytocin rau hauv koj cov hlab ntsha. Cov oxytocin nkag mus rau koj lub tsev menyuam thiab txhawb kev ua haujlwm.
Cov uterine contractions, nyob rau hauv lem, ua rau koj lub caj pas pituitary tso tawm ntau oxytocin, ua rau muaj kev nce rau hauv ob qho tib si siv thiab zaus ntawm contractions. Oxytocin kuj tseem ua rau kev tsim cov prostaglandins (ib pab pawg ntawm lipids nrog cov tshuaj hormone-zoo li kev ua), uas ua rau muaj zog ua haujlwm thiab ua rau muaj kev sib kis ntau dua. Qhov no ua rau koj ua tiav qhov chaw mos tag nrho.
Oxytocin Levels tswj
Oxytocin yog ib qho ntawm ob peb cov tshuaj hormones uas muaj cov lus pom zoo. Qhov no txhais tau hais tias kev tso tawm ntawm oxytocin ua rau cov kev ua uas ua rau koj lub caj pas pituitary tso tawm ntau dua.
Feem ntau cov tshuaj hormones tsim cov kev tawm tswv yim tsis zoo tom qab lawv tso tawm, txhais tau tias koj lub cev tso tawm cov tshuaj hormones tsawg dua tom qab nws muaj kev cuam tshuam rau koj lub cev.
Nrog uterine contractions thaum yug me nyuam, lub siab ntawm koj lub tsev me nyuam ntawm tus me nyuam hauv plab nkoos koj lub pituitary kom tso tawm oxytocin. Kev tso tawm txuas ntxiv mus txog thaum koj tus menyuam yug los. Nrog rau lactation thiab pub niam mis, koj tus menyuam qhov nqus tau txhawb koj lub pituitary kom tso tawm oxytocin los thawb cov mis los ntawm koj lub mis. Qhov kev tso tawm txuas ntxiv mus txog thaum koj tus menyuam tsis pub noj thiab yuav rov pib dua thaum koj tus menyuam noj dua.
Autism Spectrum Disorder thiab Social Behavior Research
- Intranasal Oxytocin hauv Autism Spectrum Disorder Studies
Intranasal oxytocin tau raug sim hauv ASD vim tias oxytocin signaling, kev paub txog kev sib raug zoo, thiab oxytocin receptor gene tau kawm txog kev puas hlwb. Ib qho meta- kev tshuaj ntsuam tau tshaj tawm txog kev sib koom ua ke ntawm OXTR kev hloov pauv thiab kev puas siab puas ntsws spectrum, tab sis kev koom nrog caj ces tsis ua pov thawj tias kev kho oxytocin txhim kho cov tsos mob.
Cov txiaj ntsig kho mob sib txawv. A 2023 ob -dig muag randomized sim hauv tsev kawm ntawv- cov menyuam hnub nyoog tau siv 12 IU ob zaug hauv ib hnub rau 4 lub lis piam thiab pom kev txhim kho hauv ob pawg oxytocin thiab placebo, tab sis kev txhim kho tsis yog tshwj xeeb rau intranasal oxytocin thaum lub sijhawm ob - dig muag theem 19.
- Oxytocin hauv cov menyuam yaus, cov neeg laus, cov txiv neej, thiab cov poj niam koom nrog
Oxytocin hauv cov menyuam yaus, cov neeg laus, cov neeg koom nrog txiv neej, thiab cov poj niam koom nrog yuav tsis muaj qhov cuam tshuam zoo ib yam. Kev tshuaj xyuas ntawm kev tshawb fawb intranasal oxytocin txheeb xyuas qhov sib txawv ntawm kev sib deev, cov yam ntxwv ntawm lub hauv paus, kev kuaj mob ntawm lub hlwb, kev xaiv cov txiaj ntsig, thiab kev rov tsim dua li cov teeb meem loj rau kev sim siab yav tom ntej.
Qhov no yog tshwj xeeb tshaj yog muaj feem xyuam rau hauv kev tshawb fawb menyuam yaus. Ib qho kev sim 2021 NEJM hauv cov menyuam yaus thiab cov tub ntxhais hluas nrog ASD tsis pom muaj txiaj ntsig kev sib raug zoo lossis kev paub txog kev paub txawm tias lub sijhawm kho 24 lub lis piam, thiab cov xwm txheej tsis zoo feem ntau zoo sib xws ntawm pab pawg.
- Vim li cas Social Outcomes yog qhov nyuaj los ntsuas kev ntseeg siab
Cov txiaj ntsig ntawm kev sib raug zoo yog qhov nyuaj los ntsuas vim "kev ua haujlwm hauv zej zog" suav nrog kev saib xyuas, kev paub txog kev xav, kev pom qhov muag, kev txhawb siab, kev sib txuas lus, kev coj cwj pwm rov ua dua, kev saib xyuas tus neeg saib xyuas, thiab kev sib cuam tshuam hauv ntiaj teb tiag. Ib qho kev hloov pauv ntawm ib txoj haujlwm hauv chav kuaj yuav tsis txhais ua txhua hnub - txhim kho lub neej.
Oxytocin kuj tsis tsuas yog ua kom muaj kev coj tus cwj pwm zoo. Kev tshuaj xyuas nco ntsoov tias oxytocin tuaj yeem ua rau muaj kev ntxhov siab hauv zej zog thiab tuaj yeem muaj kev cuam tshuam sib txawv nyob ntawm cov ntsiab lus ntawm kev sib raug zoo, suav nrog hauv -pab pawg / tawm - pab pawg neeg mob thiab kev hem thawj rau kev xav.
Cov pov thawj Preclinical thiab Kev txhais lus txwv
Cov pov thawj preclinical txhawb nqa oxytocin qhov tseem ceeb hauv cov tsiaj txhu hauv kev coj noj coj ua, kev yug me nyuam, thiab neural signaling, tab sis kev tshawb pom tsiaj tsis tuaj yeem kho raws li cov pov thawj ntawm tib neeg kev kho mob. Cov kev txwv kev txhais lus yog qhov tseem ceeb tshwj xeeb rau cov lus thov coj tus cwj pwm.
Tsiaj qauv, Oxytocin Receptor-Ntsuas nas, thiab tus cwj pwm
Cov qauv tsiaj txhu tau pab txheeb xyuas txoj hauv kev ntawm oxytocin receptor, kev sib raug zoo - paub txog qhov tshwm sim, kev yug me nyuam lub cev, thiab neural - lub luag haujlwm hauv lub voj voog. Oxytocin receptor-cov nas tsis muaj peev xwm thiab lwm yam kev sim ua qauv muaj txiaj ntsig zoo rau kev tshawb pom cov txheej txheem, tab sis lawv tsis tuaj yeem teb seb puas muaj oxytocin intranasal txhim kho cov txiaj ntsig ntawm tib neeg kev sib raug zoo.
Amygdala, Ventral Tegmental Cheeb Tsam, thiab Kev Tshawb Fawb Txog Kev Tshawb Fawb
Kev tshawb fawb Oxytocin nquag tshuaj xyuas cov amygdala, ventral tegmental cheeb tsam, nucleus accumbens, thiab lwm yam khoom plig los yog salience circuits. Hauv kev tshawb fawb fMRI tib neeg, intranasal oxytocin txo txoj cai -ib sab amygdala cov lus teb rau lub ntsej muag lub siab, txhawb lub luag haujlwm hauv kev sib raug zoo- kev xav.
Cov txiaj ntsig muaj peev xwm
Kev coj tus cwj pwm, kev ntseeg, kev xav, thiab tib neeg kev sib raug zoo
Oxytocin koom nrog hauv kev coj noj coj ua thiab kev sib raug zoo ntawm tib neeg, tab sis qhov kev thov txiaj ntsig tsis yooj yim. Intranasal oxytocin nce kev ntseeg tus cwj pwm hauv xyoo 2005 tib neeg kev ntseeg siab-kev sim ua si, thaum tom qab kev tshawb fawb pom tias cov teebmeem oxytocin tuaj yeem nyob ntawm cov ntsiab lus, cov hauv paus ntsiab lus, kev sib raug zoo, thiab kev kawm tsim.
Lactation, Reproduction, and Sexual Behavior Research Context
Oxytocin yog lub hauv paus rau cov kua mis ejection thiab uterine contraction. NCBI kev pub niam mis physiology piav qhia tias oxytocin ua rau cov hlwb myoepithelial nyob ib ncig ntawm daim ntawv cog lus alveoli, txav cov mis los ntawm cov ducts thaum lub sij hawm letdown reflex 15.
Oxytocin kuj tau tham txog hauv kev yug me nyuam thiab kev sib deev - kev tshawb fawb txog tus cwj pwm, suav nrog lub luag haujlwm hauv ejaculation thiab kev sib raug zoo, tab sis kev thov kev kho mob rau libido, kev sib deev, lossis kev sib raug zoo yuav tsum muaj pov thawj muaj zog ntau dua li kev siv lub cev ib leeg.
FAQ
Retatrutide Powder siv rau dab tsi?
Koj tuaj yeem ua rau oxytocin tso tawm hauv cov poj niam los ntawm kev sib raug zoo hauv zej zog, kov lub cev, thiab kev ntxhov siab - txo cov dej num.
oxytocin ua dab tsi rau koj?
Oxytocin yog ib qho tshuaj hormones thiab tshuaj lom neeg hauv koj lub hlwb uas ua rau muaj kev sib raug zoo, kev ntseeg siab, thiab lub cev ua haujlwm zoo li kev yug menyuam.
Vim li cas oxytocin hu ua tshuaj hlub?
Oxytocin yog hu ua "kev hlub tshuaj" lossis "kev hlub hormone" vim tias koj lub cev tso tawm thaum lub cev kov, kev sib deev, thiab kev yug menyuam los txhawb kev sib raug zoo, kev ntseeg siab, thiab kev hlub.
oxytocin ua dab tsi rau ib tug txiv neej?
Oxytocin cuam tshuam rau tus txiv neej lub cev thiab lub hlwb los ntawm kev txhawb nqa kev sib deev, kev sib raug zoo ntawm kev xav, thiab txo kev ntxhov siab.
Yog tias koj tab tom nrhiav rau siab - zooOxytocin hmoovcov chaw tsim khoom uas koj tuaj yeem tsim kom muaj sijhawm ntev -, kev sib koom tes ruaj khov, ces Shaanxi Medibridge Biotech Co., Ltd. yuav yog koj tus khub lag luam zoo tshaj plaws. Tsis txhob yig tiv tauj peb ntawmhi@medibridgeapi.com.
Cim npe nrov: Tuam Tshoj oxytocin hmoov manufacturers, lwm tus neeg, Hoobkas
