Dihydroquercetin hmoov

Antioxidant Mechanism

Phenolic hydroxyl pawg ncaj qha scavenge ntau reactive dawb-radicals nrog rau DPPH, ABTS, superoxide anions thiab hydroxyl radicals. Lub caij no, lawv nce- tswj txoj hauv kev Nrf2/ARE thiab txhawb kev nthuav tawm ntawm endogenous antioxidant proteins (HO-1, SOD, GSH). Nws exerts dual teebmeem ntawm ncaj qha dawb-radical quenching thiab endogenous antioxidant activation. Piv nrog rau ntau lwm cov flavonoids, nws muaj cov hlau muaj zog -chelating muaj peev xwm thiab inhibits hlau-mediated lipid peroxidation.

Muaj peev xwm dawb radical Scavenging: nplua nuj nyob rau hauv 5 phenolic hydroxyl pawg (tshwj xeeb tshaj yog B-ring catechol qauv), nws muaj txiaj ntsig pub hydrogen atoms kom tsis txhob muaj cov pa oxygen reactive (ROS), superoxide anions (O2-), thiab hydroxyl radicals (OH). Nws Oxygen Radical Absorbance Capacity (ORAC) nyob rau ntawm qhov siab tshaj plaws ntawm ntuj flavonoids.

Hloov Hlau Ion Chelation: Chelates hloov pauv hlau ions xws li Fe2+ thiab Cu2+, zoo thaiv cov tshuaj tiv thaiv Fenton thiab inhibiting lipid peroxidation thiab malondialdehyde (MDA) tiam ntawm qhov chaw.

Endogenous Antioxidant Enzyme Ua kom muaj zog: Ua kom Nrf2-YOG txoj kev taw qhia, txhawb nqa cov noob qhia ntawm endogenous antioxidant enzymes suav nrog heme oxygenase-1 (HO-1), superoxide dismutase (SOD), thiab glutathione peroxidase (GSH-Px).

Inflammatory Cascade Suppression: Qhov cuam tshuam tseem ceeb ntawm kev ua kom NF-kB (Nuclear Factor-kB) thiab MAPKs taw qhia txoj hauv kev, yog li txo qis cov kev qhia ntawm pro-inflammatory cytokines (TNF-alpha, IL-1beta, IL-6) thiab CO2 inflammatory, IL-6s).

Metabolic & Lipid Regulation: Ua kom txoj hauv kev AMPK, modulating lipid metabolism, alleviating insulin resistance, thiab txo cov kab mob siab triglyceride tsub zuj zuj - qhia txog kev kho muaj peev xwm tiv thaiv tsis yog - kab mob cawv fatty siab (NAFLD) thiab metabolic syndrome.

Apoptosis Induction & Anti-Kev loj hlob: Hauv kev tshawb fawb oncology tsom, nws tswj hwm Bcl-2 / Bax tsev neeg cov proteins thiab suppresses PI3K / Akt / mTOR txoj hauv kev los ntxias lub voj voog ntawm tes thiab tsom apoptosis hauv ntau cov kab mob.

Tiv thaiv vascular endothelial hlwb, tiv thaiv oxidative kev hloov pauv ntawm qis - ntom lipoprotein (LDL), thiab txhawb nqa nitric oxide (NO) synthesis kom nthuav cov hlab ntsha, txhim kho microcirculation, thiab txo cov ischemia - raug mob reperfusion.

Neuroprotection (Brain Health)

Hla cov ntshav-brain barrier (BBB) ​​kom txo tau cov neuronal oxidative stress, inhibit amyloid-beta (A\\beta) aggregation, thiab suppress Tau protein hyperphosphorylation- ua rau nws yog ib tus neeg sib tw tseem ceeb hauv Alzheimer's disease (AD) thiab cerebral ischemia research.

Hepatoprotective & Raum Repair

Qhia txog kev kho cellular tseem ceeb thiab tiv thaiv cov tshuaj lom neeg -induced lossis yeeb tshuaj-induced hepatorenal toxicity.

• Pharmaceuticals & Nutraceuticals

Kev siv dav siv los ua cov khoom siv raw hauv kev mob plawv, kev tiv thaiv kab mob, thiab kev tiv thaiv kev laus - cov tshuaj tiv thaiv kev laus thoob plaws Tebchaws Europe (EU Novel Food tau pom zoo), Asmeskas (GRAS tau ntawv pov thawj), thiab Russia.

• Cosmeceuticals

Ua hauj lwm raws li ib tug muaj zog antioxidant thiab soothing active nyob rau hauv anti-photoaging, brightening/anti-spot (tyrosinase inhibition), thiab rhiab heev - daim tawv nqaij barrier formulations.

• Khoom noj khoom haus & Lipid Preservation

Siv los ua cov tshuaj antioxidant zoo heev hauv cov roj unsaturated- cov roj nplua nuj, nqaij, thiab cov khoom siv mis nyuj kom txuas ntxiv cov khoom txee lub neej.