98 Polydatin hmoov

Dawb Radical Scavenging & Hlau Chelation

Muaj cov tsiaj muaj zog reactive oxygen (ROS) thiab reactive nitrogen hom (RNS) cov peev txheej pov tseg, thaum tiv thaiv lipid peroxidation tshwm sim los ntawm Fenton cov tshuaj tiv thaiv.

Ua kom muaj Sirt1 / Nrf2 Signaling Pathway

Muaj peev xwm ua kom SIRT1 (Sirtuin 1) thiab Nrf2-YOG yog cov teeb liab hloov pauv antioxidant, txhawb kev qhia muaj zog ntawm endogenous superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), thiab heme oxygenase-1 (HO-1).

Mitochondrial Quality Control

Stabilizes mitochondrial membrane muaj peev xwm, inhibits kev tso tawm ntawm Cytochrome c los ntawm mitochondria, txo mitochondria -mediated apoptosis, thiab tiv thaiv cellular zog metabolism nyob rau hauv siab - kev nyuaj siab.

Kev Tiv Thaiv NF-kB & NLRP3 Inflammasome

Blocks NF-kB nuclear translocation thiab NLRP3 inflammasome los ua ke, txo qis kev tso tawm ntawm pro-inflammatory cytokines (TNF-\\alpha, IL-1\\beta, IL-6, IL-18) thiab PGE_2.

Cardiovascular & Endothelial Protection

inhibits kev loj hlob txawv txav thiab kev tsiv teb tsaws ntawm vascular du leeg hlwb (VSMCs), txhawb nqa endothelial nitric oxide synthase (eNOS) qhia kom tso tsis tau, nthuav cov hlab ntsha, thiab txo qis myocardial ischemia- rov ua dua raug mob thiab atherosclerosis.

Neuroprotection & Hepatorenal Preservation

Hla cov ntshav-brain barrier (BBB) ​​kom txo qis microglia-mediated neuroinflammation; Ua kom pom kev tiv thaiv tseem ceeb thiab txo qis cov tshuaj toxicity, tsis yog - cawv fatty siab kab mob (NAFLD), thiab hyperuricemia hauv daim siab thiab lub raum raug mob qauv.

Glucolipid Metabolism Modulation

Ua kom lub AMPK (AMP-activated protein kinase) txoj hauv kev los txhim kho cov tshuaj insulin thiab txo cov roj cholesterol tag nrho (TC), triglycerides (TG), thiab qis-cov roj lipoprotein ceev (LDL{2}}C) qib.

Induction ntawm Tumor Cell Apoptosis

Hauv kev txiav -ntug tiv thaiv- kev tshawb fawb qog nqaij hlav, polydatin downregulates Bcl-2 thaum txhim kho Bax thiab Caspase-3/9, inducing cell voj voog ntes thiab tsom apoptosis hauv cov hlwb, nrog rau inhibiting qog angiogenesis.

Khoom noj khoom haus & Khoom noj khoom haus ntuj

Ua haujlwm zoo tshaj plaws rau kev noj qab haus huv ntawm cov hlab plawv, tiv thaiv -aging, qaug zog, thiab tiv thaiv daim siab, dav siv rau hauv cov tshuaj ntsiav, ntsiav tshuaj, thiab dej haus.

Cosmeceuticals

Muaj kev tshwj xeeb los tiv thaiv- yees duab, ci ntsa iab (ntawm tyrosinase thiab melanin synthesis inhibition), thiab soothing / anti- kev ua xua, ua rau nws ua haujlwm tseem ceeb rau siab - kawg los tiv thaiv - kev laus, whitening serums, thiab cov txheej txheem kho qhov teeb meem.

Pharmaceutical API Development

Raws li cov khoom siv tshuaj muaj txiaj ntsig zoo, nws ua rau pom kev hloov pauv tau zoo hauv kev tshawb fawb cuam tshuam nrog kev txhaj tshuaj hauv cov hlab ntsha, txhawb nqa -tso tawm tshuab, thiab cov neeg nqa khoom (xws li liposomes thiab nanoparticles).