Liquiritigenin hmoovyog ib tug natural compound teej tug mus rau phytochemical chav kawm hu ua flavonoids. Nws yog muab los ntawm lub hauv paus ntawm licorice (Glycyrrhiza glabra), tshuaj ntsuab txhua xyoo nyob rau thaj tsam Mediterranean thiab thaj tsam ntawm Asia. Liquiritigenin paub txog nws cov khoom siv tshuaj ntau yam thiab tau siv rau hauv cov tshuaj ib-paus xyoo.
Ib qho ntawm cov yam ntxwv tseem ceeb ntawm liquiritigenin yog nws cov haujlwm antioxidant. Antioxidants ua lub luag haujlwm tseem ceeb hauv lub cev los ntawm kev tshem tawm cov teeb meem dawb radicals thiab cov molecules tsis ruaj khov uas tuaj yeem ua rau puas hlwb thiab ua rau muaj ntau yam kab mob, suav nrog mob qog noj ntshav, kab mob plawv, thiab neurodegenerative disorders. Liquiritigenin ua raws li antioxidant los ntawm kev tshem tawm cov dawb radicals thiab tiv thaiv cov hlwb los ntawm oxidative kev nyuaj siab.
Shaanxi Medibridge Biotech Co., Ltd., Ltd. muab cov nroj tsuag rho tawm, cov khoom noj khoom haus, thiab cov khoom siv tshwj xeeb rau cov khoom sib txawv thiab kev xav tau. Peb txhawb nqa cov khoom ruaj khov, cov kev qhia tshwj xeeb niaj hnub sib xws, thiab cov kev pabcuam ntim hloov tau yooj yim rau cov khoom xyaw - raws li kev tsim khoom.
COA
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Khoom npe |
CAS Nr |
Batch Number |
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Liquiritigenin hmoov |
578-86-9 |
MB2604150224 |
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Hnub tim tsim khoom |
Hnub Soj Ntsuam |
Hnub Kawg |
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2026/4/15 |
2026/4/16 |
2028/4/15 |
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Qauv Qty Puag |
Ntim |
Txoj Kev Xeem |
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120 KGS |
25KG / nruas |
HPLC |
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Yam khoom |
Txuj |
Cov txiaj ntsig |
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Qhov tshwm sim |
Dawb crystalline hmoov |
Ua raws |
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Assay |
98% |
98.36% |
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tsw & saj |
Yam ntxwv |
Yam ntxwv |
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Particle loj |
100% txog 80 mesh |
80 mesh |
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Tshauv |
Tsawg dua los yog sib npaug li 0.5% |
0.06% |
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Poob rau ziab |
Tsawg dua lossis sib npaug li 1.0% |
0.27% |
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Hnyav hlau |
Tsawg dua lossis sib npaug li 15ppm |
3ppm ua |
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Cadmium (Cd) |
Tsawg dua los yog sib npaug li 0.5ppm |
Ua raws |
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Lead (Pb) |
Tsawg dua lossis sib npaug li 1ppm |
Ua raws |
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Arsenic (As) |
Tsawg dua lossis sib npaug li 2ppm |
Ua raws |
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Mercury (Hg) |
Tsis zoo |
Tsis zoo |
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Tag nrho cov kab mob suav |
Tsawg dua lossis sib npaug li 1000cfu / g |
67cfu/g ib |
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Fungi |
Tsawg dua lossis sib npaug li 100cfu / g |
12 cfu/g |
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Samonella |
Tsis zoo |
Tsis zoo |
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E. Coli |
Tsis zoo |
Tsis zoo |
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Xaus |
Cov batch ua raws li IN-HOUSE tus qauv |
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Botanical Source thiab Production
Liquiritigenin tuaj yeem raug cais tawm ntawm cov nroj tsuag ntawm Glycyrrhiza genus lossis tsim los ntawm hydrolyzing liquiritin. Cov txheej txheem luam tawm suav nrog kev rho tawm hydrolytic ua raws li siab - nrawm nrawm chromatography, nrog rau kev hloov pauv enzymatic siv -glucosidase.
Cov khoom muag raws li "Liquiritigenin Powder" yuav txawv heev. Ib qho yuav yog ib qho siab -purity cais tawm; Lwm qhov yuav yog licorice extract standardized rau cov ntsiab lus liquiritigenin; ib feem peb yuav muaj cov neeg nqa khoom los txhim kho kev tuav lossis tawg. Ib qho tshwj xeeb ntawm 98% liquiritigenin yog li sib txawv ntawm licorice extract uas muaj 5% liquiritigenin.
Mechanisms
Estrogen Receptor Beta Activity
Hauv cov txheej txheem sim, liquiritigenin tau nyiam qhib ER - cov lus teb hloov pauv hloov kho tau. Cov hauj lwm tom ntej tau tshawb xyuas seb tus cwj pwm receptor thiab kev nrhiav neeg ua haujlwm ntawm cov proteins uas tswj hwm qhov kev xaiv no. Cov kev tshawb pom no ua rau liquiritigenin pab tau rau kev kawm ER signaling. Lawv tsis tsim kom muaj kev ua haujlwm tshwj xeeb los ntawm ER ntawm txhua qhov kev xav lossis hauv txhua cov ntaub so ntswg, lossis tias nws yog kev kho tshuaj estrogen zoo.
Inflammatory Signaling
Hauv lipopolysaccharide-stimulated macrophage qauv, liquiritigenin txo NF-κB activation, inducible nitric oxide synthase (iNOS), thiab zus tau tej cov pro-inflammatory cytokines. Ib txoj kev tshawb nrhiav nas colitis kuj tau qhia txog kev txhim kho ntawm qhov mob -txog kev ntsuas.
Oxidative Stress thiab daim siab ua qauv
Cov kev tshawb fawb tau txuas liquiritigenin rau NRF2 cov lus teb antioxidant thiab txhim kho oxidative - kev ntsuas kev ntxhov siab hauv cov xov tooj ntawm tes thiab tsiaj cov qauv ntawm lub siab raug mob. Ib txoj kev tshawb fawb 2023 tau tshuaj xyuas NRF2 kev ua kom muaj feem nrog KEAP1 thiab p62. Cov txiaj ntsig zoo li no cuam tshuam rau kev tshawb nrhiav tshuaj; lawv tsis yog pov thawj tias liquiritigenin kho tib neeg daim siab kab mob.
Tshawb nrhiav cov lus qhia thiab cov pov thawj qib
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Tshawb nrhiav thaj chaw |
Cov pov thawj sawv cev |
Kev txhais lus tsim nyog |
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ER thiab poj niam's noj qab haus huv |
Receptor, cell, thiab cov ntaub so ntswg tshawb fawb |
Ib tus neeg sib tw rau kev tshawb nrhiav tshuab; nyem ntawm cov tsos mob menopausal tsis yog tsim los rau cov khoom sib cais |
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Kev mob |
Macrophage thiab tsiaj kab mob qauv |
Lub hauv paus rau kev tshawb fawb ntxiv thiab kev tsim qauv |
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Oxidative kev nyuaj siab thiab kev tiv thaiv lub siab |
Cell thiab tsiaj raug mob qauv |
Cov ntaub ntawv pov thawj rau kev tshawb nrhiav NRF2-txog cov txheej txheem |
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Cancer{0}}kev tshawb fawb txog |
Cell, tsiaj txhu, thiab txwv tib neeg- tshawb fawb cov ntaub so ntswg |
Kev tshawb fawb hypothesis, tsis yog tsim los tiv thaiv kab mob |
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Khoom noj khoom haus, tshuaj pleev ib ce, lossis kev txhim kho ntxiv |
Nyob ntawm cov khoom tshwj xeeb thiab npaj siv |
Yuav tsum tau cais kev nyab xeeb, kev ruaj ntseg, thiab kev ntsuas kev tswj hwm |
Kev Tswj Xyuas Zoo
- Kev Qhia Txog Tus Kheej: Botanical hom thiab cog ib feem, txheej txheem tsim khoom, sib piv nrog cov qauv siv, thiab cov ntaub ntawv txheeb xyuas cov qauv tsim nyog.
- Kev ntsuam xyuas thiab qhov tsis huv: HPLC lossis UPLC kev ntsuas ntawm liquiritigenin, nrog rau kev tshaj tawm cais ntawm liquiritin, isoliquiritigenin, thiab cov ntsiab lus tsis pom tseeb.
- Cov txheej txheem residues thiab cov khoom tsis huv: Kev ntsuam xyuas tsim nyog rau cov txheej txheem rho tawm thiab ua kom huv, suav nrog cov kuab tshuaj residual, cov hlau hnyav, tshuaj tua kab, thiab kev txwv microbial.
- Powder thiab formulation zog: Particle loj, noo noo, batch sib xws, tus cwj pwm nyob rau hauv lub npaj formulation, thiab stability nyob rau hauv lub teeb, kub, thiab av noo tej yam kev mob.
- Glycyrrhizin residue: Sib cais thaum cov khoom siv los ntawm licorice extraction lossis hydrolysis. Kev ntsuam xyuas liquiritigenin siab ib leeg tsis qhia tias glycyrrhizin tau raug tshem tawm.
Kev nyab xeeb thiab kev thov
Vim liquiritigenin muaj cov tshuaj estrogen -receptor- cuam tshuam txog kev ua haujlwm hauv kev sim, qhov ncauj lossis lwm yam siab - raug siv lav kev soj ntsuam kev nyab xeeb, tshwj xeeb tshaj yog rau kev siv sijhawm ntev -, cev xeeb tub lossis pub niam mis, thiab cov neeg uas muaj tshuaj hormones - cov kab mob rhiab heev. Cov pov thawj muaj cuab yeej siv tsis tau tsim kom muaj kev nyab xeeb rau tib neeg cov tshuaj liquiritigenin hmoov.
Cov kev pheej hmoo ntawm purified liquiritigenin kuj tseem yuav raug cais tawm ntawm cov khoom seem hauv cov licorice - muab cov khoom xyaw. Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv Hauv Tebchaws Meskas tau sau tseg tias glycyrrhizin hauv licorice tuaj yeem ua rau muaj kev phom sij loj hauv qee yam mob, suav nrog cov teeb meem ntsig txog ntshav siab, qib poov tshuaj, thiab lub plawv dhia. Rau qhov ncauj siv licorice- tau txais cov hmoov, glycyrrhizin residue yuav tsum tau ntsuas es tsis xav tias tsis tuaj.
Kev soj ntsuam tag nrho: Liquiritigenin hmoov yog qhov zoo tshaj plaws uas yog cov nroj tsuag - muab cov kev tshawb fawb muaj txiaj ntsig nrog lub hauv paus kev sim muaj txiaj ntsig hauv ER teeb liab, o, thiab oxidative stress. Nws qhov tsim nyog rau cov khoom tiav yog nyob ntawm qhov kev qhia meej meej, cov khoom siv rov ua tau zoo, cov ntaub ntawv raug rau txoj kev npaj siv, thiab tib neeg cov pov thawj tsim nyog rau cov lus thov.
FAQ
Cov txiaj ntsig ntawm licorice hmoov yog dab tsi?
Licorice hmoov muaj zog tiv thaiv - inflammatory thiab soothing zog uas pab ua kom lub plab zom mov, txo qhov mob caj pas, thiab txhim kho daim tawv nqaij noj qab haus huv.
Peb puas tuaj yeem haus cov hmoov licorice txhua hnub?
Kev haus dej licorice hmoov txhua hnub feem ntau tsis pom zoo rau lub sijhawm ntev yam tsis muaj kev saib xyuas kev kho mob vim muaj kev pheej hmoo ntawm cov kev mob tshwm sim loj.
Puas yog licorice hmoov zoo rau cov tawv nqaij dawb?
Yog lawm, licorice hmoov pab ua kom pom qhov tsaus ntuj thiab txawm tawm ntawm daim tawv nqaij, txawm tias nws tsis hloov koj cov xim ntawm daim tawv nqaij.
Lub npe INCI rau licorice extract yog dab tsi?
Lub npe INCI rau ntshiab licorice extract yog Glycyrrhiza Glabra (Licorice) hauv paus Extract.
Yog tias koj tab tom nrhiav rau siab - zooLiquiritigenin hmoovcov chaw tsim khoom uas koj tuaj yeem tsim kom muaj sijhawm ntev -, kev sib koom tes ruaj khov, ces Shaanxi Medibridge Biotech Co., Ltd. yuav yog koj tus khub lag luam zoo tshaj plaws. Tsis txhob yig tiv tauj peb ntawmhi@medibridgeapi.com.
Cim npe nrov: Liquiritigenin hmoov, Tuam Tshoj liquiritigenin hmoov manufacturers, lwm tus neeg, Hoobkas
