Cyanotis Arachnoidea Extract hmoov

Cyanotis arachnoidea CB Clarke belongs rau tsev neeg Commelinaceae thiab feem ntau faib nyob rau hauv siab - thaj chaw siab ntawm Yunnan thiab Sichuan, Suav.

High Enrichment yam ntxwv: Muab piv rau lwm cov nroj tsuag uas muaj ecdysteroids xws li spinach (Spinacia oleracea) lossis Achyranthes bidentata (qhov twg cov ntsiab lus qhuav qhuav yog feem ntau<0.1%), the 20-hydroxyecdysone (20E) content in the dry weight of whole herb or roots of Cyanotis arachnoidea can reach as high as 1.5%–5.0%. This makes it the most extraction-efficient and cost-effective raw material source currently available.

Cov Koom Haum Me Nyuam Yaus: Ntxiv rau nws cov ntsiab lus tseem ceeb, 20-hydroxyecdysone cov extract kuj muaj cov qauv me me xws li rubrosterone thiab polypodine B.

Cov hmoov sib txawv ntawm lub teeb- daj mus rau xim av- xim av zoo li. Raws li phytoecdysteroid, -ecdysterone nta dej solubility zoo thiab kuj yog soluble hauv ethanol thiab methanol, txawv ntawm tsis zoo -soluble polyphenols xws li resveratrol.

- Kev ruaj ntseg:

Thermostable nyob rau hauv nruab nrab thiab tsis muaj zog- acidic tej yam kev mob; Cov txheej txheem degradation tshwm sim nyob rau hauv muaj zog - alkaline ib puag ncig los yog ntev ntev - kub raug.

- Industrial workflow:

Aqueous / ethanolic extraction, macroporous resin enrichment, recrystallization purification thiab tshuaj tsuag- ziab. Cyanotis arachnoidea sawv cev rau qhov tseem ceeb ntawm kev lag luam botanical qhov chaw rau kev lag luam -qib -ecdysterone, yielding ntau dua ecdysterone cov ntsiab lus tshaj lwm cov nroj tsuag xws li Achyranthes bidentata los yog podocarpus hom.

- Kev sib txawv zoo:

Tag nrho -spectrum extract muaj ntau yam ecdysterone homologues; siab-purity monomer (Ntau dua lossis sib npaug li 90%) yog tswj hwm los ntawm -ecdysterone nrog tsawg impurities.

• Anabolic txoj kev rau cov protein thiab pob txha-cov leeg nqaij metabolism

-ecdysterone tsis khi rau mammalian estrogen lossis androgen receptors. Nws qhib lub PI3K/Akt/mTOR signaling cascade, nce - tswj ribosomal protein qhia, txhawb skeletal-cov leeg nqaij protein synthesis thiab suppresses protein degradation los pab txhawb myocyte proliferation. Qhov no muab cov txiaj ntsig anabolic yam tsis muaj endocrine sab- cuam tshuam rau cov tshuaj hormones steroid.

• Antioxidant Nrf2 txoj kev

Nws scavenges reactive oxygen hom (ROS), ua rau Keap1-Nrf2 txoj hauv kev thiab txhawb nqa endogenous antioxidant enzymes suav nrog SOD thiab GSH-Px, yog li txo qis oxidative kev nyuaj siab thiab kev tawm dag zog ua rau oxidative puas tsuaj.

• Anti-inflammatory kev cai

Nws inhibits NF-κB taw qhia txoj hauv kev thiab nqes- tswj cov pro- cov neeg kho mob inflammatory xws li TNF- thiab IL-6. Nws txo qis kev tawm dag zog-provoked muscular o thiab mob, thiab ameliorates qis-qib inflammatory xeev.

• Pob txha-Kev hloov pauv ntawm cov metabolism

Nws txhawb nqa osteoblast proliferation thiab nce alkaline phosphatase (ALP) kev ua haujlwm; lub caij no nws txwv kev sib txawv ntawm cov pob txha thiab pob txha resorption, ua tiav cov kev cai bidirectional ntawm pob txha remodelling.

• Glucose-lipid metabolic kev hloov pauv

Nws qhib txoj hauv kev AMPK, txhim kho insulin rhiab heev thiab txhawb nqa cellular qabzib. Nws kuj modulates lipid profiles thiab txo cov rog ntau dhau.

Nws nthuav tawm qhov muaj nruab nrab ntawm qhov ncauj bioavailability thiab tsis muaj cov tshuaj steroid- cuam tshuam txog kev cuam tshuam endocrine, ua rau nws yog ib qho khoom siv zoo anabolic raw khoom.

• Kev ua si nawv thiab khaws cia cov nqaij

Qhov no yog nws thawj daim ntawv thov. Nws pab lub zog- tau txais thiab kev ua haujlwm siab, txo cov leeg nqaij catabolism nyob rau hauv siab - kev cob qhia siv zog thiab ua kom cov nqaij leeg muaj protein ntau. Feem ntau tsim ua ke nrog creatine thiab BCAAs.

• Antioxidation thiab post-kev tawm dag zog rov qab

Nws txo cov dawb-radical puas tsuaj tshwm sim los ntawm kev cob qhia lub cev, txo cov leeg nqaij inflammatory teb, ua kom lub sij hawm rov qab thiab ua kom qeeb qeeb - pib mob nqaij hlav (DOMS).

• Metabolic thiab lub cev-tswj qhov hnyav

Nws txhim kho cov tshuaj insulin rhiab heev, pab tswj lub cev -cov rog rog thiab khaws cia lub cev tsis muaj zog rau lub cev -kev sib xyaw- ua kom zoo tshaj plaws.

• Pob txha-kev txhawb nqa kev noj qab haus huv

Nws txhawb osteogenesis thiab inhibits pob txha resorption rau nruab nrab- laus thiab cov laus cov pob txha- noj qab haus huv. Muaj pov thawj muaj los ntawm cov qauv tsiaj, thaum tib neeg cov ntaub ntawv kho mob tseem khaws cia.

• Anti-laus thiab collagen-txhawb cov teebmeem

Nws txhawb nqa dermal fibroblasts los ua ke hom -Ⅰ thiab hom-Ⅲ collagen. Nws inhibits matrix metalloproteinases (MMPs) kom qeeb collagen degradation, ameliorate nplua wrinkles thiab txhim kho daim tawv nqaij firmness.

• Soothing thiab barrier-kho cov khoom

Nws nqes - tswj cov cutaneous pro- inflammatory mediators, mitigates stimulus -induced tawv nqaij redness thiab kho daim tawv nqaij barrier muaj nuj nqi. Dav dav siv hauv kev tiv thaiv- kev laus kho cov tshuaj pleev thiab cov tshuaj nplaum.

• Moisturization thiab keratin modulation

Nws maj mam tswj keratin turnover, ua kom rov ua dua tshiab ntawm cov stratum corneum puas thiab synergizes nrog humectants los kho cov tawv nqaij ntxhib.