Semaxhmoovyog ib qho hluavtaws luv peptide feem ntau piav raws li qhov ua tau zoo ntawm ACTH (4-10) ntu. Nws yog feem ntau siv hauv kev tshawb fawb ntsig txog neuropharmacology, peptide-raws li kev tshawb fawb txog kev siv tshuab, neuroprotection, thiab kev paub txog- cov txheej txheem cuam tshuam. Los ntawm kev xav txog kev tshawb fawb, tus nqi ntawm Semax txuas ntxiv dhau ntawm qhov ua haujlwm peptide ib leeg, vim nws sawv cev rau qhov zoo - lees paub luv luv -peptide qauv ntawm central neuromodulation. Raws li, nws tau raug tshawb nrhiav dav hauv cov kev tshawb fawb txog kev tswj hwm neurotransmitter, neurotrophic signaling, ischemic thiab raug mob- cuam tshuam txog kev tiv thaiv, kev kawm thiab kev nco, thiab kev hloov pauv kev ntxhov siab.
Shaanxi Medibridge muab Semax hmoov nrog 99.5% purity rau kev tshawb fawb siab heev. Custom labeling thiab formulation xaiv muaj nyob rau ntawm kev thov. Xaiv Shaanxi Medibridge rau kev ntseeg siab, kev txhawb nqa, thiab cov txiaj ntsig tau zoo hauv kev tshawb fawb neuroprotection thiab neuroplasticity.
COA
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Khoom npe |
CAS Nr |
Batch Number |
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Semax |
80714-61-0 |
MB2509651520 |
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Hnub tim tsim khoom |
Hnub Soj Ntsuam |
Hnub Kawg |
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2025/8/21 |
2025/10/12 |
2027/10/15 |
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Qauv Qty Base |
Ntim |
Txoj Kev Xeem |
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42.62 KWG |
25 Gs/BOTTLE |
HPLC |
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Yam khoom |
Txuj |
Cov txiaj ntsig |
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Purity |
Ntau dua lossis sib npaug li 98% |
99.68% |
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Peptide Assay |
Ntau dua lossis sib npaug li 80% |
91.65% |
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Solubility |
Soluble hauv dej |
Ua raws |
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Clarity thiab xim ntawm kev daws |
Ntshiab thiab tsis muaj xim |
Ua raws |
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Salt |
<5.0% |
1.75% |
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Dej |
Tsawg dua lossis sib npaug li 9.0% |
3.26% |
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Residual Solvent: Methanol |
Tsawg dua lossis sib npaug li 0.3% |
Ua raws |
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Isopropanol |
Tsawg dua los yog sib npaug li 0.5% |
Ua raws |
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Cov tshuaj acetonitrile |
Tsawg dua lossis sib npaug li 0.041% |
0.03% |
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Methylene Chloride |
Tsawg dua lossis sib npaug li 0.06% |
0.035% |
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N,N{0}}Dimethylformamide |
Tsawg dua lossis sib npaug li 0.088% |
N.D. |
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Triethylamine |
Tsawg dua lossis sib npaug li 0.032% |
N.D. |
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Tert -butyl methyl ether |
Tsawg dua los yog sib npaug li 0.5% |
0.21% |
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Endotoxin |
Tsawg dua lossis sib npaug li 0.5 EU / mg |
Ua raws |
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Microbial txwv |
Tag nrho cov kab mob aerobic<100 CFU/g |
<50 CFU/g |
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Tag nrho cov poov xab & pwm<50 CFU/g |
<10 CFU/g |
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Cia |
Khaws rau hauv qhov chaw tsaus thiab txias qhuav (-20 txog 8 degree) |
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Xaus |
Cov batch ua raws li IN-HOUSE tus qauv |
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Biological Mechanism
Neurotrophic-Txoj Kev Sib Txuas
Qhov no yog ib qho ntawm cov txheej txheem tseem ceeb tshaj plaws hauv kev tshawb fawb Semax. Kev tshawb fawb feem ntau tshuaj xyuas seb Semax cuam tshuam li cas:
- BDNF
- NGF-txoj kev cuam tshuam
- Plasticity{0}}cov noob caj noob ces
- Tom qab- kho qhov raug mob- hais txog kev taw qhia
Neurotransmitter Network Regulation
Semax kuj tau raug tshawb xyuas rau nws qhov muaj peev xwm cuam tshuam rau cov tshuab neurotransmitter, tshwj xeeb:
- Dopaminergic signaling
- Serotonergic tshuav nyiaj li cas
- Monoaminergic adaptation
Ntau dua li tsuas yog nce ib leeg neurotransmitter, Semax tuaj yeem nkag siab zoo dua li cuam tshuam rau kev hloov pauv homeostasis ntawm neurotransmitter networks.
Kev raug mob- thiab Kev Nyuaj Siab-Txoj Kev Sib Txuas
Hauv ischemia lossis kev ntxhov siab-cov qauv ntsig txog, Semax feem ntau tau kawm txog nws lub luag haujlwm tseem ceeb hauv kev tswj hwm:
- Oxidative stress markers
- Inflammatory mediators
- Kev nyuaj siab- teb cov noob
- Apoptosis- ntsig txog kev taw qhia
Classic Experimental Paradigms
Kev Kawm thiab Memory/Cognitive Behavioral Model
Kev kawm, kev nco, thiab kev paub txog tus cwj pwm coj tus cwj pwm tau siv dav hauv Semax kev tshawb fawb los ntsuas nws qhov muaj feem cuam tshuam rau siab dua - xaj neural muaj nuj nqi. Hauv cov ntsiab lus no, cov neeg tshawb xyuas feem ntau tshuaj xyuas kev ua haujlwm, kev nco qab, kev saib xyuas -txoj kev coj tus cwj pwm, thiab kev hloov kho cov lus teb raws li cov xwm txheej tsis zoo lossis kev paub tsis zoo. Cov qauv no pab txiav txim seb Semax puas cuam tshuam nrog kev paub txog kev txhawb nqa, txhim kho cov txheej txheem nco, thiab txhim kho tus cwj pwm hloov pauv, yog li muab cov pov thawj kev sim rau nws qhov tseem ceeb neurofunctional.
Cov qauv ntawm Cerebral Ischemia lossis Hypoxia
Cov qauv ntawm cerebral ischemia lossis hypoxia tau siv dav hauv Semax kev tshawb fawb los ntsuas nws qhov muaj peev xwm tiv thaiv kev cuam tshuam hauv cov xwm txheej ntawm oxygen deprivation lossis focal hlwb raug mob. Cov qauv no tso cai rau cov neeg tshawb xyuas los sib piv cov kev ua haujlwm tsis txaus, cov ntaub so ntswg puas, kev hloov pauv, thiab cov lus teb neurotrophic ua ntej thiab tom qab kev cuam tshuam. Los ntawm kev sib koom ua ke ntawm tus cwj pwm thiab cov ntsiab lus lom neeg, cov qauv no muab cov qauv kev sim rau kev txiav txim siab seb Semax puas cuam tshuam nrog kev tiv thaiv ntawm cov ntaub so ntswg tsis zoo.
Integrated PK/PD Kev Tshawb Fawb
Kev koom ua ke PK / PD cov kev tshawb fawb ntawm Semax yog qhov tseem ceeb rau kev txhais nws txoj kev hloov pauv los ntawm kev sim peptide mus rau tus neeg saib xyuas kev noj tshuaj tsis zoo. Ib koob tshuaj - lub hauv paus ntsiab lus txuas txuas cov koob tshuaj mus rau lub cev thiab qhov nruab nrab, tom qab ntawd qhia txog qhov tshwm sim ntawm lub sijhawm ntawm cov lus teb molecular, thiab thaum kawg hais txog cov kev hloov pauv no rau kev coj cwj pwm lossis kev ua haujlwm.
Qhov kev tsim no pab txheeb xyuas seb puas muaj qhov tshwm sim hauv nruab nrab, qhia meej txog qhov sib lawv liag ntawm biomarker kev hloov kho thiab kev ua tau zoo, thiab txiav txim siab lub qhov rai zoo tshaj plaws rau kev txhais cov tshuab txhais lus thiab cov qauv kev kawm txhais lus.
Derivative Design & Peptide Engineering
Semax kuj sawv cev rau peptide muaj txiaj ntsig -kev tsim kho scaffold rau kev ua kom zoo dua qub. Nws cov kab ke tso cai rau cov amino acid hloov pauv, txhim kho kev ruaj ntseg, thiab sib npaug khaws cia ntawm bioactivity thaum hloov kho cov qauv. Qhov no ua rau Semax zoo haum rau cov qauv-kev sib raug zoo kev tshawb fawb txog kev txheeb xyuas qhov sib txawv nrog kev txhim kho cov tshuaj muaj zog, kev ua haujlwm zoo, thiab muaj peev xwm txhais lus.
Kev sim ntsuas tus yam ntxwv
Tsis txhob saib qhov nominal purity xwb.
High purity tsis cia li lav txhim khu kev qha cov ntsiab lus zoo thiab batch zoo; Cov ntsiab lus peptide tseem ceeb sib npaug.
Peptides yog nquag degradation ua ntej kev sim.
Yog tias qhov chaw khaws cia, rov tsim kho, lossis khov -thaw cycles tsis raug tswj kom zoo, cov qauv yuav raug cuam tshuam ua ntej qhov kev sim tiag tiag.
Yuav tsum paub txog cov yas adsorption.
Cov peptides luv luv xws li Semax tuaj yeem nqus tau rau saum npoo ntawm cov khoom siv yas xws li cov raj centrifuge thiab cov lus qhia pipette, ua rau txo qis hauv kev ua haujlwm zoo.
Ua tib zoo mloog rau endotoxins hauv kev sim tshuaj lom neeg.
Yog tias ua kev sim ntawm tes lossis tsiaj sim, nws raug nquahu kom ua tib zoo saib ntxiv rau:
- endotoxins
- tsis muaj menyuam
- lub nra microbial
Ua me me - ntsuas qhov kev sim ua ntej kev ruaj ntseg.
Ua ntej pib txoj haujlwm raug cai, nws yog qhov zoo tshaj los ua qhov luv luv - kev ntsuas kev ruaj ntseg los soj ntsuam:
- cov nyhuv ntawm lub sijhawm
- cov nyhuv pH
- cov nyhuv ntawm cov khoom ntim
- stability tom qab reconstitution
Kev Tshawb Fawb Cov Lus Qhia
Neuropharmacology thiab kev paub muaj nuj nqi
Semax tau kawm dav hauv neuropharmacology thiab kev paub txog- kev tshawb fawb txog, tshwj xeeb tshaj yog rau nws cov txiaj ntsig ntawm kev kawm, kev nco, kev saib xyuas, kev paub txog kev ua tau zoo, thiab kev hloov pauv hauv cov xwm txheej xws li qaug zog lossis kev ntxhov siab.
Neuroprotection
Semax tau txais kev txaus siab tseem ceeb hauv neuroprotection, tshwj xeeb tshaj yog nyob rau hauv cov qauv ntawm cerebral ischemia, hypoxia, neural raug mob, oxidative kev nyuaj siab, thiab inflammatory neural puas, nrog rau kev tshawb fawb tsom rau neuronal ciaj sia taus, kev raug mob markers, neurotrophic txhawb, thiab inflammatory teb.
Neurotrophic Signaling thiab Plasticity
Semax feem ntau tham txog kev cuam tshuam nrog BDNF thiab lwm yam neurotrophin-txoj kev cuam tshuam, nrog rau cov kev tshawb fawb soj ntsuam nws muaj peev xwm koom nrog hauv neural plasticity, synaptic adaptation, thiab kev saib xyuas ntawm kev ua haujlwm ntawm neural circuit stability.
Kev tswj hwm kev ntxhov siab thiab kev coj tus cwj pwm hloov
Hauv kev ntxhov siab-Txoj kev tshawb fawb txog, Semax tau siv los tshuaj xyuas cov lus teb rau tus cwj pwm mob hnyav, hloov kho kev ntxhov siab ntev, kev ntxhov siab-xws li lossis kev ntxhov siab- phenotypes rhiab heev, thiab cuam tshuam txog neuroendocrine lossis neurochemical hloov cuam tshuam rau kev hloov kho.
Kev cai Neurotransmitter
Kev tshawb fawb Semax feem ntau suav nrog cov tshuab monoaminergic, tshwj xeeb tshaj yog dopamine, serotonin, thiab norepinephrine, txhawm rau tshawb xyuas nws lub luag haujlwm tseem ceeb hauv kev tswj hwm kev sib npaug ntawm cov paj hlwb txuas nrog kev paub, kev xav, thiab kev tswj kev xav.
FAQ
Semax peptide zoo rau dab tsi?
Semax yog siv rau kev paub txog kev txawj ntse thiab kev tiv thaiv kab mob.
Puas yog Semax stimulating?
Yog, Semax yog stimulating.
Semax puas cuam tshuam nrog cov tshuaj hormones?
Semax zoo li cuam tshuam rau cov tshuaj hormones kev ntxhov siab thiab cov teeb meem neurotrophic hauv lub hlwb.
Semax puas zoo rau kev puas hlwb?
Semax nce BDNF uas txhawb kev paub txog kev ua haujlwm, neuroplasticity, thiab kev puas siab puas ntsws.
Qhov twg txhaj Semax?
Semax feem ntau yog siv raws li kev txhaj tshuaj subcutaneous (sub-Q) lossis siv intranasally.
Yog tias koj tab tom nrhiav rau lub siab - zoo Semax hmoov chaw tsim tshuaj paus nrog leej twg koj tuaj yeem tsim lub sijhawm ntev -, kev sib koom tes ruaj khov, ces Shaanxi Medibridge Biotech Co., Ltd. yuav yog koj tus khub lag luam zoo tshaj plaws. Tsis txhob yig tiv tauj peb ntawm hi@medibridgeapi.com.
Cim npe nrov: Tuam Tshoj semax hmoov manufacturers, lwm tus neeg, Hoobkas
